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Disseminated herpes simplex virus 2 as a complication of pregnancy

Lauren Bougioukas, Rachel Psoinos, David C. Jones, Erin Morris, Andrew J. Hale

2021IDCases11 citationsDOIOpen Access PDF

Abstract

Disseminated herpes simplex virus 2 (HSV-2) infection, is a rare but devastating infection in pregnancy women. We present the case of a 30-year-old gravida 3, para 2-0-0-2, at 26 weeks 2 days gestation who presented with eleven days of vague and indolent symptoms before a diagnosis of disseminated HSV-2 infection with associated hepatitis was made. While the patient clinically improved with empiric acyclovir treatment, possibility of significant harm to the fetus remained, and the patient request elective termination. The authors review the epidemiology, diagnosis, treatment, and prognosis of disseminated HSV-2 infection in pregnancy.

Topics & Concepts

MedicineHerpes simplex virusComplicationPregnancyVirologyObstetricsVirusSurgeryBiologyGeneticsHerpesvirus Infections and TreatmentsParvovirus B19 Infection StudiesHepatitis Viruses Studies and Epidemiology