Litcius/Paper detail

Synthesis of chalcone derivatives by Claisen-Schmidt condensation and <i>in vitro</i> analyses of their antiprotozoal activities

Gabriella B. Souza, Tamiris A. C. Santos, Amanda P. S. Silva, André L. B. S. Barreiros, Victória Brandão Nardelli, Ingrid Borges Siqueira, Silvio Santana Dolabella, Emmanoel Vilaça Costa, Péricles Barreto Alves, Ricardo Scher, Roberta Pereira Miranda Fernandes

2022Natural Product Research24 citationsDOI

Abstract

. The addition of a naphthyl group to the B ring can be postulated to be the cause of the 10 times increase observed in its trypanocidal activity.

Topics & Concepts

AntiprotozoalChalconeChemistryTraditional medicineIn vitroStereochemistryMedicineBiochemistryInsect and Pesticide ResearchResearch on Leishmaniasis Studies