Topology-Based Functionalization of Robust Chiral Zr-Based Metal–Organic Frameworks for Catalytic Enantioselective Hydrogenation
Hong Jiang, Wenqiang Zhang, Xing Kang, Ziping Cao, Xu Chen, Yan Liu, Yong Cui
Abstract
to support the Ir complex. Incorporation of Ir-phosphorus catalysts into Zr-MOFs leads to great enhancement of their chemical stability, durability, and even stereoselectivity. This work therefore not only advances Zr-MOFs as stable supports for labile metal catalysts for heterogeneous asymmetric catalysis but also provides a new insight into how highly active chiral centers can result due to the framework topology.
Topics & Concepts
Enantiopure drugCatalysisChemistryEnantioselective synthesisTopology (electrical circuits)Metal-organic frameworkSelectivityCombinatorial chemistryChemical stabilityAsymmetric hydrogenationSurface modificationOrganic chemistryPhysical chemistryCombinatoricsAdsorptionMathematicsMetal-Organic Frameworks: Synthesis and ApplicationsCovalent Organic Framework ApplicationsAsymmetric Hydrogenation and Catalysis