Simultaneously deplete reactive oxygen species and inhibit pyroptosis by dopamine/thioketal-containing polymers delivering disulfiram in combination with Cu(II) for acute glaucoma
Xuezhi Zhou, Rong Rong, Ganghao Liang, Haibo Li, Mengling You, Zhou Zeng, Haihua Xiao, Dan Ji, Xiaobo Xia
Topics & Concepts
PyroptosisReactive oxygen speciesChemistryIn vivoPharmacologyProgrammed cell deathApoptosisCell biologyBiochemistryBiologyBiotechnologyGlaucoma and retinal disordersInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxide