Psoralen induces hepatotoxicity by covalently binding to glutathione-S-transferases and the hepatic cytochrome P450
Min Jiang, Xiaoying Wang, Bin Lv, Yujie Lu, Xianghui Ma, Wenjuan Liu, Gang Bai, Xiumei Gao
Topics & Concepts
PsoralenGlutathioneCytochrome P450PharmacologyChemistryLiver injuryBiochemistryIn vivoCYP3A4Glutathione S-transferaseMetabolismEnzymeBiologyBiotechnologyDNABioactive natural compoundsPlant chemical constituents analysisPharmacogenetics and Drug Metabolism