From systems to structure — using genetic data to model protein structures
Hannes Braberg, Ignacia Echeverria, Robyn M. Kaake, Andrej Sali, Nevan J. Krogan
Topics & Concepts
Computational biologyBiologyProtein structureProtein–protein interactionGenetic variantsSystems biologySequence (biology)Genetic dataComputer scienceGenetic variationModel systemProtein structure predictionProtein sequencingPhenotypeNetwork structureModel organismHuman genetic variationProtein Interaction NetworksVariation (astronomy)Artificial intelligenceStructural biologyProtein domainEvolutionary biologyDeep learningGenetic modelGeneticsMutationGenomicsBiological networkInteraction networkIntrinsically disordered proteinsMachine learningSequence alignmentNetwork modelHuman geneticsProtein Structure and DynamicsBioinformatics and Genomic NetworksGenetic Associations and Epidemiology