The yeast exoribonuclease Xrn1 and associated factors modulate RNA polymerase II processivity in 5‘ and 3‘ gene regions
Jonathan Fischer, Yun S. Song, Nir Yosef, Julia di Iulio, L. Stirling Churchman, Mordechai Choder
Abstract
deletion in mRNA synthesis and were differentially regulated by mRNA decay pathways, raising the possibility that one distinction between these two gene classes lies in the mechanisms that balance mRNA synthesis with mRNA decay.
Topics & Concepts
ExoribonucleaseProcessivityGeneBiologyGeneticsYeastPolymeraseRNARNase PFungal and yeast genetics researchRNA and protein synthesis mechanismsRNA Research and Splicing