Are the processes of DNA replication and DNA repair reading a common structural chromatin unit?
Stefania Mamberti, M. Cristina Cardoso
Abstract
3D-SIM: 3D-structured illumination microscopy; 3C: chromosome conformation capture; DDR: DNA damage response; FISH: fluorescent in situ hybridization; Hi-C: high conformation capture; HiP-HoP: highly predictive heteromorphic polymer model; IOD: inter-origin distance; LAD: lamina associated domain; STED: stimulated emission depletion microscopy; STORM: stochastic optical reconstruction microscopy; SBS: strings and binders switch model; TAD: topologically associated domain.
Topics & Concepts
ChromatinChromosome conformation captureDNABiologyDNA replicationComputational biologyGenomeDNA damageGenomic organizationMicroscopyBiophysicsCell biologyPhysicsGeneticsGeneOpticsEnhancerGene expressionGenomics and Chromatin DynamicsDNA Repair MechanismsRNA and protein synthesis mechanisms