CaCO3 based proton nanosponge to potentiate immune checkpoint blockade therapy by synergistically reversing tumor immunosuppression
Hao Yu, Minming Chen, Yumin Wu, Ziliang Dong, Yujie Zhu, Chunjie Wang, Quguang Li, Zhijuan Yang, Zhuang Liu, Liangzhu Feng
Topics & Concepts
PLGAImmunosuppressionSystemic administrationCancer researchPharmacologyImmune checkpointImmune systemChemistryImmunotherapyNanomedicineMedicineImmunologyMaterials scienceNanotechnologyNanoparticleIn vivoBiochemistryBiologyIn vitroBiotechnologyCancer Immunotherapy and BiomarkersNanoplatforms for cancer theranosticsCancer, Stress, Anesthesia, and Immune Response