Litcius/Paper detail

Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects

Omnia M. Hendawy, Hesham A. M. Gomaa, Sami I. Alzarea, Mutariah S. Alshammari, Fatma A. Mohamed, Yaser A. Mostafa, Ahmed H. Abdelazeem, Mostafa Abdelrahman, Laurent Trembleau, Bahaa G. M. Youssif

2021Bioorganic Chemistry31 citationsDOI

Topics & Concepts

ChemistryCelecoxibAnti-inflammatoryPharmacologyAnalgesicPyrazoleIC50In vivoCardiotoxicityStereochemistryIn vitroBiochemistryToxicityMedicineOrganic chemistryBiologyBiotechnologyEicosanoids and Hypertension PharmacologySynthesis and biological activitySynthesis and Biological Evaluation