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Photocatalytic Redox-Neutral Approach to Diarylmethanes

Guozhe Guo, Yong Yuan, Xiazhen Bao, Xuehui Cao, Tongzhi Sang, Jiayuan Wang, Congde Huo

2021Organic Letters24 citationsDOI

Abstract

We report a visible-light induced redox-neutral decarboxylative cross coupling reaction of indole-3-acetic acid NHPI esters with indoles using a Ru photosensitizer to deliver a wide range of symmetrical and unsymmetrical 3,3'-bisindolylmethane derivatives. Furthermore, the reaction is readily adapted to the preparation of a wide variety of diarylmethane derivatives.

Topics & Concepts

ChemistryRedoxPhotosensitizerPhotocatalysisIndole testPhotochemistryAcetic acidCombinatorial chemistryElectrochemistryCatalysisOrganic chemistryElectrodePhysical chemistrySynthesis of Indole DerivativesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions
Photocatalytic Redox-Neutral Approach to Diarylmethanes | Litcius