Physiologically based pharmacokinetic (PBPK) modeling for prediction of celecoxib pharmacokinetics according to CYP2C9 genetic polymorphism
Young‐Hoon Kim, Pureum Kang, Chang‐Keun Cho, Eui Hyun Jung, Hye‐Jeong Park, Yun Jeong Lee, Jung‐Woo Bae, Choon‐Gon Jang, Seok‐Yong Lee
Topics & Concepts
Physiologically based pharmacokinetic modellingCelecoxibPharmacokineticsCYP2C9PharmacologyMedicinePharmacogeneticsGenotypeChemistryInternal medicineCytochrome P450BiochemistryMetabolismGeneInflammatory mediators and NSAID effectsPharmacogenetics and Drug MetabolismEicosanoids and Hypertension Pharmacology