FOXM1 inhibitor, Siomycin A, synergizes and restores 5-FU cytotoxicity in human cholangiocarcinoma cell lines via targeting thymidylate synthase
Nathakan Klinhom-on, Wunchana Seubwai, Kanlayanee Sawanyawisuth, Sumalee Obchoei, Panupong Mahalapbutr, Sopit Wongkham
Topics & Concepts
Thymidylate synthaseCytotoxicityCancer researchFOXM1Cell cultureChemistryMolecular biologyBiologyCellBiochemistryFluorouracilChemotherapyIn vitroCell cycleGeneticsFOXO transcription factor regulationCholangiocarcinoma and Gallbladder Cancer StudiesColorectal Cancer Treatments and Studies