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Severe organising pneumonia following COVID-19

István Vadász, Faeq Husain‐Syed, Peter Dorfmüller, Fritz Roller, Khodr Tello, Matthias Hecker, Rory E. Morty, Stefan Gattenlöhner, Hans-Dieter Walmrath, Friedrich Grimminger, Susanne Herold, Werner Seeger

2020Thorax90 citationsDOIOpen Access PDF

Abstract

Various forms of diffuse parenchymal lung disease have been proposed as potential consequences of severe COVID‑19. We describe the clinical, radiological and histological findings of patients with COVID‑19-associated acute respiratory distress syndrome who later developed severe organising pneumonia including longitudinal follow-up. Our findings may have important implications for the therapeutic modalities in the late-phase of severe COVID‑19 and might partially explain why a subgroup of COVID‑19 patients benefits from systemic corticosteroids.

Topics & Concepts

MedicinePneumoniaCoronavirus disease 2019 (COVID-19)Intensive care medicine2019-20 coronavirus outbreakAcute respiratory distressSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ARDSCryptogenic Organizing PneumoniaRadiological weaponLungRespiratory distressDiseasePathologyInternal medicineSurgeryInfectious disease (medical specialty)OutbreakRespiratory Support and MechanismsLong-Term Effects of COVID-19COVID-19 Clinical Research Studies
Severe organising pneumonia following COVID-19 | Litcius