Electrochemical intramolecular N(sp<sup>2</sup>)–H/N(sp<sup>3</sup>)–H coupling for the synthesis of 1<i>H</i>-indazoles
Qiang Zhong, Pei-Long Wang, Hui Gao, Fang Ma, Youqing Yang, Hongji Li
Abstract
The electrochemical intramolecular cyclization of ketimines via N–H/N–H dehydrogenation coupling has been established for the construction of 1 H -indazole scaffolds.
Topics & Concepts
Intramolecular forceElectrochemistryDehydrogenationChemistryCoupling (piping)IndazoleMedicinal chemistryStereochemistryOrganic chemistryMaterials sciencePhysical chemistryCatalysisElectrodeMetallurgyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsCO2 Reduction Techniques and Catalysts