Comparison of synbiotics combined with enteral nutrition and prophylactic antibiotics as supportive care in patients with esophageal cancer undergoing neoadjuvant chemotherapy: A multicenter randomized study
Masaaki Motoori, Keijiro Sugimura, Koji Tanaka, Osamu Shiraishi, Yutaka Kimura, Hiroshi Miyata, Makoto Yamasaki, Tomoki Makino, Yasuhiro Miyazaki, Mitsuru Iwama, Kotaro Yamashita, Mai Niikura, Takuya Sugimoto, Takashi Asahara, Kazumasa Fujitani, Takushi Yasuda, Yuichiro� Doki, Masahiko Yano
Topics & Concepts
MedicineInternal medicineSynbioticsGastroenterologyChemotherapyAntibioticsNeutropeniaTolerabilityFebrile neutropeniaAdverse effectRandomized controlled trialDiarrheaMucositisEsophageal cancerIncidence (geometry)Clinical endpointEnteral administrationAntibiotic-associated diarrheaParenteral nutritionCancerProbioticClostridium difficileMicrobiologyPhysicsGeneticsBiologyBacteriaOpticsEsophageal Cancer Research and TreatmentGut microbiota and healthNeutropenia and Cancer Infections