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The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription

Ryo Hisada, Nobuya Yoshida, Masataka Umeda, Catalina Burbano, Rhea Bhargava, Marc Scherlinger, Michihito Kono, Vasileios C. Kyttaris, Suzanne Krishfield, George C. Tsokos

2022Cellular and Molecular Immunology28 citationsDOIOpen Access PDF

Topics & Concepts

SIRT2AutoimmunitySirtuinRAR-related orphan receptor gammaHistone deacetylaseTranscription factorInterleukin 17PathogenesisImmunologyHistoneBiologyCancer researchCell biologyChemistryAcetylationInflammationFOXP3GeneAntibodyImmune systemGeneticsSystemic Lupus Erythematosus ResearchCytomegalovirus and herpesvirus researchCytokine Signaling Pathways and Interactions
The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription | Litcius