Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss
Chong Cui, Daqi Wang, Bowei Huang, Fang Wang, Yuxin Chen, Jun Lv, Luping Zhang, Lei Han, Dong Liu, Zheng‐Yi Chen, Geng‐Lin Li, Huawei Li, Yilai Shu
Abstract
and offer a promising strategy for the treatment of KCNQ4-related deafness.
Topics & Concepts
CRISPRGenome editingCas9Hearing lossHair cellGenetic enhancementIn vivoBiologyCochleaComputational biologyNeuroscienceGeneticsGeneMedicineAudiologyHearing, Cochlea, Tinnitus, GeneticsRNA regulation and diseaseCRISPR and Genetic Engineering