Cutaneous T-cell Lymphoma and Concomitant Atopic Dermatitis Responding to Dupilumab
Nicholas Mollanazar, Kevin T. Savage, Bobak Pousti, Neha Jariwala, Christina Guzzo, Paul Haun, Carmela C. Vittorio, Alain H. Rook, Ellen J. Kim
Abstract
Cutaneous T-cell lymphoma (CTCL) represents a diagnostic challenge because of its large symptomatic overlap with other common skin conditions such as atopic dermatitis (AD) and psoriasis. Dupilumab has offered promising results in AD treatment; however, concerns exist that its use may exacerbate undiagnosed CTCL. We present a patient with CTCL and concomitant AD who experienced improvement in both CTCL blood involvement and AD following the addition of dupilumab therapy.
Topics & Concepts
DupilumabMedicineAtopic dermatitisLymphomaConcomitantDermatologyCutaneous T-cell lymphomaDiseaseImmunologyMycosis fungoidesPathologyInternal medicineCutaneous lymphoproliferative disorders researchDermatology and Skin DiseasesNail Diseases and Treatments