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CoronaVac can induce the production of anti-SARS-CoV-2 IgA antibodies in human milk

Valdenise Martins Laurindo Tuma Calil, Patrícia Palmeira, Yingying Zheng, Vera Lúcia Jornada Krebs, Werther Brunow de Carvalho, Magda Carneiro‐Sampaio

2021Clinics29 citationsDOIOpen Access PDF

Abstract

To the Editor, Human milk is the external secretion with the highest immunoglobulin A (IgA) concentrations, mostly produced in the lamina propria of mammary glands by plasma cells (). The milk antibody repertoire is quite similar to the one observed in the blood; however, the levels of antibodies against enteric and respiratory pathogens are usually higher in the colostrum and mature milk than in the serum. Maternal immunization can elicit systemic immunoglobulin G (IgG) and mucosal IgA, IgM, and IgG [...]

Topics & Concepts

ColostrumAntibodySecretory IgAImmunologyLamina propriaImmunoglobulin AImmunizationImmunoglobulin GBiologyImmune systemEpitheliumGeneticsCOVID-19 Impact on ReproductionInfant Nutrition and HealthNeonatal Respiratory Health Research