Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus
Dong An, Xiuting Qi, Kunpeng Li, Weixing Xu, Yue Wang, Xi Chen, Sha Sha, Chunfeng Wu, Yimei Du, Lei Chen
Topics & Concepts
TRPV4HMGB1Status epilepticusPharmacologyTLR4Hippocampal formationChemistryAgonistInflammationNeuroinflammationSignal transductionEpilepsyMedicineReceptorEndocrinologyNeuroscienceInternal medicineBiologyTransient receptor potential channelBiochemistryIon Channels and ReceptorsNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research