Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
Parya Kazemzadeh, Khalil Sayadi, Ali Toolabi, Jalil Sayadi, Malihe Zeraati, Narendra Pal Singh Chauhan, Ghasem Sargazi
Abstract
Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties. Silica’s unique mesoporous structure allows for effective drug loading and controlled release at the target site. In this review, we have discussed various methods of MSNs’ mechanism, properties, and its drug delivery applications. As a result, we came to the conclusion that more in vivo biocompatibility studies, toxicity studies, bio-distribution studies and clinical research are essential for MSN advancement.
Topics & Concepts
BiocompatibilityMesoporous silicaDrug deliveryNanotechnologyMesoporous materialNanoparticleMaterials scienceDrugChemistryPharmacologyOrganic chemistryMedicineCatalysisMetallurgyMesoporous Materials and CatalysisNanoparticle-Based Drug DeliveryNanoparticles: synthesis and applications