An unusual mixed-valence cobalt dimer as a catalyst for the anti-Markovnikov hydrophosphination of alkynes
Pardeep Kumar, Asmita Sen, Gopalan Rajaraman, Maheswaran Shanmugam
Abstract
A Co dimer with a 3e-reduced NNN pincer ligand [(PMe 3 ) 2 Co II (L 1 3− )Co I (PMe 3 ) 3 ] is an efficient catalyst for the hydrophosphination reaction of both internal and terminal alkynes including α-hydroxy-functionalized alkyne substrates with excellent stereo- and regioselectivity.
Topics & Concepts
Markovnikov's ruleRegioselectivityDimerCatalysisChemistryAlkyneCobaltMedicinal chemistryStereochemistryPolymer chemistryOrganic chemistryCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesOrganometallic Complex Synthesis and Catalysis