Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics
Soumya Ranjan Mishra, Kewal Kumar Mahapatra, Bishnu Prasad Behera, Srimanta Patra, Chandra Sekhar Bhol, Debasna Pritimanjari Panigrahi, Prakash Priyadarshi Praharaj, Amruta Singh, Shankargouda Patil, Rohan Dhiman, Sujit K. Bhutia
Topics & Concepts
InflammasomeMitophagyPyrin domainCell biologyMitochondrionCaspase 1NeuroinflammationProgrammed cell deathBiologyAIM2AutophagyChemistryInflammationImmunologyBiochemistryApoptosisInflammasome and immune disordersAutophagy in Disease and TherapyHeme Oxygenase-1 and Carbon Monoxide