Double CRISPR/Cas12a-drived hyperbranched rolling circle amplification with triple signal amplification enables low background miRNA detection
Shiying Zhou, Meilin Liu, Liyuan Deng, Yue Qiu, Tao Gu, Jian Chen, Mei Yang, Danqun Huo, Changjun Hou
Topics & Concepts
CRISPRRolling circle replicationBiologyGeneticsGeneDNA replicationCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery