Dissecting the heterogeneity of the alternative polyadenylation profiles in triple-negative breast cancers
Lei Wang, Guan‐Tian Lang, Mengzhu Xue, Yang Liu, Li Chen, Ling Yao, Xiaoguang Li, Peng Wang, Xin Hu, Zhi‐Ming Shao
Abstract
Our findings advance the understanding of tumor heterogeneity regulation in APA and yield new insights into therapeutic target identification in TNBC.
Topics & Concepts
Triple-negative breast cancerTriple negativeBreast cancerCancer researchComputational biologyBiologyMedicineOncologyGeneticsCancerRNA Research and SplicingCancer-related gene regulationHER2/EGFR in Cancer Research