LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
Marie O’Connor, David Kallenberg, Carlotta Camilli, Camilla Pilotti, Athina Dritsoula, René Jackstadt, Chantelle Bowers, H. Angharad Watson, Markella Alatsatianos, Julia Ohme, Laura Dowsett, Jestin George, Jack Blackburn, Xiaomeng Wang, Mahak Singhal, Hellmut G. Augustin, Ann Ager, Owen J. Sansom, Stephen E. Moss, John Greenwood
Topics & Concepts
Tumor microenvironmentCancer researchBlockadeMedicineImmune checkpointImmunotherapyImmune systemCancer immunotherapyAngiogenesisAntibodyPericyteImmunologyEndothelial stem cellReceptorBiologyInternal medicineIn vitroBiochemistryClusterin in disease pathologyInflammation biomarkers and pathwaysFerroptosis and cancer prognosis