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DeepDose: Towards a fast dose calculation engine for radiation therapy using deep learning

C Kontaxis, G.H. Bol, J.J.W. Lagendijk, Bas W. Raaymakers

2020Physics in Medicine and Biology111 citationsDOIOpen Access PDF

Abstract

grid spacing while 10 patients were used for validation. For another 11 independent test patients, the network was able to accurately estimate the segment doses from the clinical plans of each patient passing the clinical QA when compared with the Monte Carlo calculations, yielding on average 99.9%±0.3% for the forward calculated patient plans at 3%/3 mm gamma tests. Dose prediction using the trained network was very fast at approximately 0.9 seconds for the input generation and 0.6 seconds for single GPU inference per segment and 1 minute per patient in total. The overall performance of this dose calculation framework in terms of both accuracy and inference speed, makes it compelling for online adaptive workflows where fast segment dose calculations are needed.

Topics & Concepts

Monte Carlo methodCollimatorComputer scienceDeep learningConvolution (computer science)Linear particle acceleratorGround truthRadiation treatment planningData setArtificial intelligenceNuclear medicineRadiation therapyBeam (structure)MathematicsMedicineArtificial neural networkStatisticsRadiologyPhysicsOpticsAdvanced Radiotherapy TechniquesMedical Imaging Techniques and ApplicationsAdvanced X-ray and CT Imaging
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