Parkin, an E3 Ubiquitin Ligase, Plays an Essential Role in Mitochondrial Quality Control in Parkinson’s Disease
Xiaole Wang, Sitong Feng, Zhen‐Zhen Wang, Yu‐He Yuan, Nai‐Hong Chen, Yi Zhang
Topics & Concepts
ParkinPINK1MitophagyUbiquitin ligaseBiologyMitochondrial DNAParkinson's diseaseMitochondrionMitochondrial biogenesisGeneticsParkinsonismMutationUbiquitinCell biologyDiseaseNeuroscienceMedicineAutophagyGenePathologyApoptosisAutophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology