Tolerance in the Age of Immunotherapy
Jeffrey A. Bluestone, Mark S. Anderson
Abstract
The immune system distinguishes between “self” and “nonself” and remembers dangerous exposures. Elaborate mechanisms control immune responses, but in some cases, the response either does not recognize the danger or causes unwanted autoinflammation. The authors review advances in developing durable immune tolerance.
Topics & Concepts
Immune systemImmunotherapyImmunologyImmune toleranceMedicineImmune Cell Function and InteractionT-cell and B-cell ImmunologyDiabetes and associated disorders