Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer
Zhenzhen Deng, Ning Wu, Qishan Suo, Jing Wang, Yue Yang, Lihua Geng, Quanbin Zhang
Topics & Concepts
Cancer researchFucoidanTumor microenvironmentPI3K/AKT/mTOR pathwayColorectal cancerImmune systemMacrophageTumor-associated macrophageCancerBiologyMedicineImmunologyIn vitroSignal transductionCell biologyInternal medicineBiochemistryPolysaccharideSeaweed-derived Bioactive CompoundsImmune cells in cancerEchinoderm biology and ecology