Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging
Meiyang Li, Hongzhi Guo, Michael Carey, Chengyang Huang
Topics & Concepts
EpigeneticsBiologyProgenitor cellNeural stem cellStem cellCell biologyStem cell theory of agingProgenitorDownregulation and upregulationDNA methylationAdult stem cellPopulationCellular differentiationGene expressionGeneticsGeneStem cell factorMedicineEnvironmental healthNeurogenesis and neuroplasticity mechanismsMicroRNA in disease regulationEpigenetics and DNA Methylation