Long-term follow-up assessment of cardiac safety in SAFE-HEaRt, a clinical trial evaluating the use of HER2-targeted therapies in patients with breast cancer and compromised heart function
Katia Khoury, Filipa Lynce, Ana Barac, Xue Geng, Chau T. Dang, Anthony F. Yu, Karen L. Smith, Christopher Gallagher, Paula R. Pohlmann, Raquel Nunes, Pia Herbolsheimer, Robert Warren, Monvadi B. Srichai, Mark Hofmeyer, Federico M. Asch, Ming Tan, Claudine Isaacs, Sandra M. Swain
Topics & Concepts
MedicineEjection fractionBreast cancerPertuzumabTrastuzumabHeart failureCardiotoxicityInternal medicineAsymptomaticClinical endpointMetastatic breast cancerCancerCardiac function curveTargeted therapyOncologyCardiologyClinical trialSurgeryChemotherapyChemotherapy-induced cardiotoxicity and mitigationHER2/EGFR in Cancer ResearchAdvanced Breast Cancer Therapies