Transforming a toxic drug into an efficacious nanomedicine using a lipoprodrug strategy for the treatment of patient-derived melanoma xenografts
Linlin Shi, Yuchen Wang, Qinchuan Wang, Zhinong Jiang, Lulu Ren, Yepiao Yan, Zhaoxue Liu, Jianqin Wan, Lingling Huang, Beini Cen, Weidong Han, Hangxiang Wang
Topics & Concepts
CabazitaxelIn vivoPharmacologyProdrugNanomedicineDrugToxicityPharmacokineticsLiposomeDrug deliveryMedicineChemistryBiologyNanotechnologyInternal medicineCancerMaterials scienceBiochemistryProstate cancerAndrogen deprivation therapyOrganic chemistryBiotechnologyNanoparticleNanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryNanoplatforms for cancer theranostics