Excessive DNA damage mediates ECM degradation via the RBBP8/NOTCH1 pathway in sporadic aortic dissection
Zeyi Zhou, Yan Liu, Shijuan Gao, Mei Zhou, Feiran Qi, Ningyu Ding, Junmeng Zhang, Ruisha Li, Junxia Wang, Jian Shi, Ronghuang Yu, Yali Wang, Yulin Li, Jun Pan, Jie Du, Dongjin Wang
Topics & Concepts
DNA damageTranscriptomeDownregulation and upregulationCell biologyGene knockdownBiologyDNA repairImmunostainingExtracellular matrixGene expressionGeneCancer researchMolecular biologyDNAImmunologyGeneticsImmunohistochemistryRNA modifications and cancerAortic Disease and Treatment ApproachesAortic aneurysm repair treatments