Litcius/Paper detail

Fast protein analysis enabled by high-temperature hydrolysis

Yuchen Wang, Wenpeng Zhang, Zheng Ouyang

2020Chemical Science20 citationsDOIOpen Access PDF

Abstract

A high-temperature microreaction system is developed for fast and selective hydrolysis of proteins, enabling direct analysis of protein biomarkers by mass spectrometry.

Topics & Concepts

HydrolysisMass spectrometryChemistryChromatographyCombinatorial chemistryNanotechnologyMaterials scienceBiochemistryAdvanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsProtein purification and stability