HFIP-assisted reductive C–S, C–N, and C–X coupling of carbonyl compounds: a combined computational and experimental mechanistic study
Jabir Khan, Aparna Tyagi, Dibyajyoti Ghosh, Chinmoy Kumar Hazra
Abstract
Owing to the importance of carbon–heteroatom bonds in synthetic organic chemistry and pharmaceuticals, developing reliable and catalyst-free methods for their construction sets a significant goal of high practical value for modern chemistry.
Topics & Concepts
ChemistryHeteroatomCatalysisCombinatorial chemistryCoupling (piping)Computational chemistryOrganic chemistryRing (chemistry)MetallurgyMaterials scienceSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions