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Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science

Ritesh Gautam, Ian Geniza, Scott T. Iacono, Chadron M. Friesen, Abby R. Jennings

2022Molecules20 citationsDOIOpen Access PDF

Abstract

Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a variety of applications, from straightforward chemical synthesis to more advanced functions, such as fluorinated networks and polymers. This can be directly attributed to the highly reactive nature of PFPy, especially towards nucleophilic aromatic substitution (SNAr). The aim of this review is to highlight the discovery and synthesis of PFPy, discuss its reactive nature towards SNAr, and to summarize known reports of the utilization and thermal analysis of PFPy containing fluoropolymers and fluorinated network materials.

Topics & Concepts

Nucleophilic aromatic substitutionChemistryDrug discoveryPolymerNanotechnologyCombinatorial chemistryOrganic chemistryNucleophilic substitutionMaterials scienceBiochemistryFluorine in Organic ChemistrySynthesis and properties of polymersInorganic Fluorides and Related Compounds
Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science | Litcius