A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy
Kai-Xuan Zhang, Bo Wang, Wenyan Li, Yang Song, Tian Song, Yanan Li, Yu‐Bin Dong
Abstract
A covalent organic framework-based multifunctional nanomedicine, Pt@COF-BDP , can convert H 2 O 2 to O 2 and promote singlet oxygen production, thereby enhancing photodynamic therapy.
Topics & Concepts
Singlet oxygenPhotodynamic therapyCovalent organic frameworkNanomedicineCovalent bondNanoscopic scaleBODIPYNanotechnologyMaterials scienceHypoxia (environmental)ChemistryPhotochemistryOxygenNanoparticleOrganic chemistryFluorescenceQuantum mechanicsPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced Nanomaterials in Catalysis