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A class of independently evolved transcriptional repressors in plant RNA viruses facilitates viral infection and vector feeding

Lulu Li, Hehong Zhang, Changhai Chen, Hai‐Jian Huang, Xiaoxiang Tan, Zhongyan Wei, Jun‐Min Li, Fei Yan, Chuan‐Xi Zhang, Jianping Chen, Zongtao Sun

2021Proceedings of the National Academy of Sciences68 citationsDOIOpen Access PDF

Abstract

all have transcriptional repressors that interact in plants with the key components of jasmonic acid (JA) signaling, namely mediator subunit OsMED25, OsJAZ proteins, and OsMYC transcription factors. These transcriptional repressors can directly disassociate the OsMED25-OsMYC complex, inhibit the transcriptional activation of OsMYC, and then combine with OsJAZ proteins to cooperatively attenuate the JA pathway in a way that benefits viral infection. At the same time, these transcriptional repressors efficiently enhanced feeding by the virus insect vectors by repressing JA signaling. Our findings reveal a common strategy in unrelated plant viruses in which viral transcriptional repressors hijack and repress the JA pathway in favor of both viral pathogenicity and vector transmission.

Topics & Concepts

BiologyRepressorViral evolutionGeneticsTranscriptional regulationTranscription (linguistics)Psychological repressionRNAVirologyGeneTranscription factorComputational biologyGene expressionLinguisticsPhilosophyPlant Virus Research StudiesInsect-Plant Interactions and ControlPlant Parasitism and Resistance
A class of independently evolved transcriptional repressors in plant RNA viruses facilitates viral infection and vector feeding | Litcius