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HIF-independent oxygen sensing via KDM6A regulates ferroptosis

Alexander M. Minikes, Pei Liu, Hua Wang, Jiachen Hu, Hanan Alwaseem, Yueming Li, Xuejun Jiang

2025Molecular Cell21 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDemethylaseHistoneCell biologyCancer cellTranscription factorProgrammed cell deathGPX4Lipid peroxidationCancer researchBiochemistryEnzymeGeneCancerGlutathioneGeneticsApoptosisGlutathione peroxidaseCancer, Hypoxia, and MetabolismRNA modifications and cancerFerroptosis and cancer prognosis
HIF-independent oxygen sensing via KDM6A regulates ferroptosis | Litcius