The Role of <i>luxS</i> in Campylobacter jejuni Beyond Intercellular Signaling
Dina Ramić, Blaž Jug, Katarina Šimunović, Magda Tušek Žnidarič, Urban Kunej, Nataša Toplak, Minka Kovač, Marjorie Fournier, Polona Jamnik, Sonja Smole Možina, Anja Klančnik
Abstract
Campylobacter jejuni is the world's leading foodborne bacterial pathogen of gastrointestinal disease in humans. C. jejuni is a fastidious but widespread organism and the most frequently reported zoonotic pathogen in the European Union since 2005. This led us to believe that C. jejuni , which is highly sensitive to stress factors (starvation and oxygen concentration) and has a low growth rate, benefits significantly from the luxS gene.
Topics & Concepts
BiochemistryCampylobacter jejuniCitric acid cycleBiologyMutantMetabolic pathwayHomoserineAmino acid synthesisTranscriptomeMetabolismAmino acidQuorum sensingGeneGene expressionBacteriaGeneticsVirulenceLysineSalmonella and Campylobacter epidemiologyAquaculture disease management and microbiotaBacteriophages and microbial interactions