Pangenome analysis of Enterobacteria reveals richness of secondary metabolite gene clusters and their associated gene sets
Omkar S. Mohite, Colton J. Lloyd, Jonathan M. Monk, Tilmann Weber, Bernhard Ø. Palsson
Abstract
The presented workflow opens up the possibility to discover novel secondary metabolites, better understand their physiological roles, and provides a guide to identify and analyze BGC associated gene sets.
Topics & Concepts
GeneGenomeBiologyComputational biologyIn silicoBacterial genome sizeGeneticsGenomics and Phylogenetic StudiesMicrobial Natural Products and BiosynthesisMicrobial Metabolic Engineering and Bioproduction