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SEW2871 attenuates ANIT-induced hepatotoxicity by protecting liver barrier function via sphingosine 1-phosphate receptor-1–mediated AMPK signaling pathway

Tingting Yang, Xue Wang, Yi Zhou, Qiongna Yu, Heng Cai, Hao Yang, Zihang Yuan, Yingying Miao, Yuanyuan Chai, Ziteng Wu, Lixin Sun, Xin Huang, Bing Liu, Zhenzhou Jiang, Luyong Zhang

2021Cell Biology and Toxicology18 citationsDOI

Topics & Concepts

Liver injurySphingosineAMPKHepatocyteTight junctionChemistryCell biologyCholestasisSignal transductionSphingosine-1-phosphatePharmacologyEndocrinologyReceptorBiologyPhosphorylationBiochemistryProtein kinase AIn vitroDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentSphingolipid Metabolism and Signaling
SEW2871 attenuates ANIT-induced hepatotoxicity by protecting liver barrier function via sphingosine 1-phosphate receptor-1–mediated AMPK signaling pathway | Litcius