Recent advances in covalent organic frameworks (COFs) for wound healing and antimicrobial applications
Fatemeh Mohajer, Ghodsi Mohammadi Ziarani, Alireza Badiei, Siavash Iravani, Rajender S. Varma
Abstract
a covalent bond have been studied for improving wound healing and dressing applications due to their long-standing antibacterial properties. Several COF-based systems have been planned for controlled drug delivery with wound healing purposes, targeting drugs to efficiently inhibit the growth of pathogenic microorganisms at the wound spot. In addition, COFs can be deployed for combinational therapy using photodynamic and photothermal antibacterial therapy along with drug delivery for healing chronic wounds and bacterial infections. Herein, the most recent advancements pertaining to the applications of COF-based systems against bacterial infections and for wound healing are considered, concentrating on challenges and future guidelines.