Brain-wide neural dynamics of poststroke recovery induced by optogenetic stimulation
Shahabeddin Vahdat, Arjun V. Pendharkar, Terrance Chiang, Sean Harvey, Haruto Uchino, Zhijuan Cao, Anika Kim, ManKin Choy, Hansen Chen, Hyun Joo Lee, Michelle Cheng, Jin Hyung Lee, Gary K. Steinberg
Abstract
presynaptic axonal terminals in the corticothalamic circuit. Selective stimulation of the corticothalamic circuit was sufficient to improve functional recovery. Together, these findings suggest early involvement of corticothalamic circuit as an important mediator of poststroke recovery.
Topics & Concepts
OptogeneticsNeuroscienceStimulationBrain stimulationDynamics (music)MedicineBiologyPsychologyPedagogyPhotoreceptor and optogenetics researchNeuroscience and Neural EngineeringNeural dynamics and brain function