A mass spectrometry-based proteome map of drug action in lung cancer cell lines
Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang, Xuan Mo, Oleg Ursu, Matthew Christopher, Rafael B. Fernandez, Li Zheng, Brian D. Dill, Huijun Wang, Yuting Xu, Andy Liaw, Jonathan D. Mortison, Nirodhini S Siriwardana, Brian M. Andresen, Meir Glick, James R. Tata, Victoria Kutilek, Iván Cornella‐Taracido, An Chi
Topics & Concepts
ProteomeProteomicsComputational biologyProteostasisChemistryMechanism of actionDrug discoveryDrug actionMass spectrometryDrugStable isotope labeling by amino acids in cell cultureBiologyBiochemistryPharmacologyIn vitroGeneChromatographyAdvanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathwaysMass Spectrometry Techniques and Applications