The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death
B Krümmel, Thomas Plötz, Anne Jörns, Sigurd Lenzen, Ilir Mehmeti
Topics & Concepts
GPX4Phospholipid-hydroperoxide glutathione peroxidaseProgrammed cell deathApoptosisLipid peroxidationChemistryGlutathione peroxidaseCell biologyBiologyOxidative stressBiochemistryCatalaseFerroptosis and cancer prognosisImmune cells in cancerAdenosine and Purinergic Signaling