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A rapid HPLC–MS/MS method for the simultaneous determination of luteolin, resveratrol and their metabolites in rat plasma and its application to pharmacokinetic interaction studies

Wenying Wu, Kexin Li, Chen Zhao, Xiaohua Ran, Yu Zhang, Tianhong Zhang

2022Journal of Chromatography B37 citationsDOI

Topics & Concepts

ChemistryChromatographyLuteolinBioavailabilityProtein precipitationGlucuronideElectrospray ionizationPharmacokineticsFormic acidSelected reaction monitoringAnalyteQuercetinMetaboliteTandem mass spectrometryMass spectrometryPharmacologyBiochemistryAntioxidantMedicineSirtuins and Resveratrol in MedicineToxin Mechanisms and ImmunotoxinsPharmacological Effects of Natural Compounds
A rapid HPLC–MS/MS method for the simultaneous determination of luteolin, resveratrol and their metabolites in rat plasma and its application to pharmacokinetic interaction studies | Litcius