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Preclinical development and a phase 1 trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer

Weijia Fang, Zhengmao Lu, Jing Ge, Shuangshuang Zhang, Rui Zheng, Weiwei Yin, Ruidong Hao, Minmin Sun, Tianhang Luo

2025Molecular Therapy7 citationsDOI

Topics & Concepts

MedicineAdverse effectInternal medicineTargeted therapyCancerGastroenterologyOncologyImmunotherapyRefractory (planetary science)Immune systemClinical trialSurgeryImmunologyAstrobiologyPhysicsCAR-T cell therapy researchVirus-based gene therapy researchImmunotherapy and Immune Responses
Preclinical development and a phase 1 trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer | Litcius